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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG6
All Species:
22.12
Human Site:
S596
Identified Species:
54.07
UniProt:
Q86US8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86US8
NP_060045.4
1419
160462
S596
D
N
Q
E
L
Q
L
S
N
L
L
S
R
D
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548319
1527
171816
S704
D
N
Q
E
L
Q
L
S
N
L
L
S
R
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P61406
1418
160477
S595
D
N
Q
E
L
Q
L
S
N
L
L
S
R
D
R
Rat
Rattus norvegicus
NP_001099278
1472
165733
S649
D
N
Q
E
L
Q
L
S
N
L
L
S
R
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509588
959
106964
R205
G
K
E
R
G
E
S
R
A
G
E
K
S
P
S
Chicken
Gallus gallus
XP_001234885
1419
159567
S628
G
N
Q
E
Q
Q
L
S
N
L
L
S
R
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696418
1546
172554
S713
D
S
Q
E
L
Q
L
S
N
L
L
S
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651321
948
108473
C194
L
I
N
W
K
N
F
C
Y
I
H
D
Q
L
Q
Honey Bee
Apis mellifera
XP_393289
1688
192186
A856
L
L
L
D
I
E
R
A
D
L
E
L
Q
W
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794411
1745
199805
G765
E
R
K
G
R
R
R
G
S
S
E
A
E
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
85.5
N.A.
90.8
88
N.A.
40.7
69.6
N.A.
49.3
N.A.
21.7
29.7
N.A.
24.4
Protein Similarity:
100
N.A.
N.A.
88.7
N.A.
95.1
91.9
N.A.
49.8
80.3
N.A.
64.4
N.A.
36.2
45.5
N.A.
41.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
86.6
N.A.
86.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
100
N.A.
20
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
10
0
0
0
0
10
0
0
10
0
50
0
% D
% Glu:
10
0
10
60
0
20
0
0
0
0
30
0
10
20
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
10
10
0
0
10
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
10
10
0
10
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
20
10
10
0
50
0
60
0
0
70
60
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
50
10
0
0
10
0
0
60
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
60
0
10
60
0
0
0
0
0
0
20
0
10
% Q
% Arg:
0
10
0
10
10
10
20
10
0
0
0
0
60
0
60
% R
% Ser:
0
10
0
0
0
0
10
60
10
10
0
60
10
0
20
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _